Several studies have tested the efficacy of lifestyle interventions to reduce excess GWG. ConclusionsĬompared with standard care, lifestyle interventions initiated in pregnancy and focused on healthy eating, increased physical activity, and other behavioral strategies resulted in significantly less weight retention but similar infant anthropometric outcomes at 12 months postpartum in a large, diverse US population of women with overweight and obesity.Įxcess gestational weight gain (GWG) is associated with several adverse pregnancy outcomes and is a well-established risk factor for high maternal postpartum weight retention and greater offspring BMI through childhood and adolescence. There was no statistically significant treatment group effect on infant anthropometric outcomes at 12 months.
36.2%) at or below baseline weight at 12 months postpartum (yes/no) compared with standard care. Lifestyle intervention also significantly increased the odds (OR = 1.68 (95% CI, 1.26, 2.24)) and percentage of mothers (48.2% vs. 0.7 ± 6.2 kg, respectively difference of −1.6 kg (95% CI −2.5, −0.7 p = 0.0003) the intervention effect was mediated by reduction in excess GWG, which explained 22% of the effect on postpartum weight retention. ResultsĬompared with standard care, lifestyle intervention reduced postpartum weight retention (2.2 ± 7.0 vs. Individual participant data were combined and analyzed using generalized linear mixed models with trial entered as a random effect. In LIFE-Moms, women ( N = 1150 14.1 weeks gestation at enrollment) with overweight or obesity were randomized within each of seven trials to lifestyle intervention or standard care.
Randomized controlled trials from the LIFE-Moms consortium investigated lifestyle interventions that began in pregnancy and tested whether there was benefit through 12 months on maternal postpartum weight retention (i.e., the difference in weight from early pregnancy to 12 months) and infant-weight-for-length z scores. Whether lifestyle interventions to reduce excess GWG also reduce 12-month maternal postpartum weight retention and infant weight-for-length z score is unknown. Excess gestational weight gain (GWG) is a risk factor for maternal postpartum weight retention and excessive neonatal adiposity, especially in women with overweight or obesity.
0 kommentar(er)
